Sex Hormone–Dependent Lipid Mediator Formation in Male and Female Mice During Peritonitis

Sex Hormone–Dependent Lipid Mediator Formation in Male and Female Mice During Peritonitis

Introduction: Sex differences in inflammation are obvious and contribute to divergences in the incidence and severity of inflammation-related diseases that frequently preponderate in women. Lipid mediators (LMs), mainly produced by lipoxygenase (LOX) and cyclooxygenase (COX) pathways from polyunsatu...

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Bibliographic Details
Main Authors: Bilancia, R. (Author), Borrelli, F. (Author), Ialenti, A. (Author), Jordan, P.M (Author), Meyer, K.P.L (Author), Pace, S. (Author), Rossi, A. (Author), Sautebin, L. (Author), Serhan, C.N (Author), Troisi, F. (Author), Werz, O. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
adult
animal experiment
animal model
arachidonate 12 lipoxygenase
arachidonate 15 lipoxygenase
arachidonate 5 lipoxygenase
arachidonate 5 lipoxygenase activating protein
Article
controlled study
cyclooxygenase 2
enzyme linked immunosorbent assay
female
inflammation
interleukin 1beta
interleukin 6
lipid mediator
lipoxygenase
liquid chromatography-mass spectrometry
male
mouse
nonhuman
peritoneum exudate
peritonitis
polyunsaturated fatty acid
prostaglandin synthase
sex difference
sex differences
sex hormone
specialized pro-resolving mediators
Western blotting
zymosan-induced peritonitis
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