Strategies for Enzymatic Inactivation of the Veterinary Antibiotic Florfenicol

Strategies for Enzymatic Inactivation of the Veterinary Antibiotic Florfenicol

Large quantities of the antibiotic florfenicol are used in animal farming and aquaculture, contaminating the ecosystem with antibiotic residues and promoting antimicrobial resistance, ultimately leading to untreatable multidrug-resistant pathogens. Florfenicol-resistant bacteria often activate expor...

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Bibliographic Details
Main Authors: Arndt, K.M (Author), Müller, M.M (Author), Nedielkov, R. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
antibiotic inactivation
antibiotic resistance
aquaculture
Article
Bacillus cereus
bacterial cell
bacterial growth
beta lactamase
chloramphenicol
chloramphenicol acetyltransferase
controlled study
cow milk
enzymatic inactivation
enzyme activity
enzyme optimization
Escherichia coli
florfenicol
fluorescence intensity
green fluorescent protein
homologous recombination
hydrolase
immobilization
immobilized metal affinity chromatography
industrial farming
nitrilotriacetate nickel
nonhuman
nuclear magnetic resonance spectroscopy
polymerase chain reaction
protein purification
protein structure
silicic acid
silicon dioxide
size exclusion chromatography
veterinary medicine
wastewater
whole milk
zone of inhibition
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