Establishment of Novel Neuroendocrine Carcinoma Patient-Derived Xenograft Models for Receptor Peptide-Targeted Therapy

Establishment of Novel Neuroendocrine Carcinoma Patient-Derived Xenograft Models for Receptor Peptide-Targeted Therapy

Gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) are rare cancers consist-ing of neuroendocrine carcinomas (NECs) and neuroendocrine tumors (NETs), which have been increasing in incidence in recent years. Few cell lines and pre-clinical models exist for studying GEP NECs and NETs, limiting...

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Main Authors: Abusada, E. (Author), Aghaamiri, S. (Author), Azhdarinia, A. (Author), Bellizzi, A.M (Author), Beyer, G.V (Author), Borbon, L.C (Author), Chan, C.H.F (Author), Cliften, P.F (Author), Ear, P.H (Author), Fields, R.C (Author), Ghosh, S.C (Author), Govindan, R. (Author), Howe, J.R (Author), Li, G. (Author), Li, R. (Author), McDonough, M. (Author), Mudd, J.L (Author), O’dorisio, M.S (Author), O’dorisio, T. (Author), Tran, C.G (Author), Vargas, S.H (Author), Wadas, T.J (Author), Walsh, S.A (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
gastroenteropancreatic neuroendocrine neoplasms
near infrared-labelled octreotide analog
patient-derived xenograft
somatostatin receptor-2
tumor spheroids
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