Platelet-Derived PDGFB Promotes Recruitment of Cancer-Associated Fibroblasts, Deposition of Extracellular Matrix and Tgfβ Signaling in the Tumor Microenvironment
Platelets constitute a major reservoir of platelet-derived growth factor B (PDGFB) and are continuously activated in the tumor microenvironment, exposing tumors to the plethora of growth factors contained in platelet granules. To address the specific role of platelet-derived PDGFB in the tumor micro...
Main Authors: | Cedervall, J. (Author), Hamidi, A. (Author), Hellman, L. (Author), Herre, M. (Author), Kamali-Moghaddam, M. (Author), Manouchehri Doulabi, E. (Author), Miao, Z. (Author), Olsson, A.-K (Author), Qiao, Q. (Author), Zhang, Y. (Author) |
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Format: | Article |
Language: | English |
Published: |
MDPI
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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