The Biogenesis of miRNAs and Their Role in the Development of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects upper and lower motor neurons. As there is no effective treatment for ALS, it is particularly important to screen key gene therapy targets. The identifications of microRNAs (miRNAs) have completely changed the traditiona...

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Main Authors:	Bao, W. (Author), Chen, Y. (Author), Guan, Y. (Author), Huo, Z. (Author), Liu, J. (Author), Meng, F. (Author), Su, Q. (Author), Wang, X. (Author), Zhang, L. (Author), Zhao, J. (Author), Zhao, Z. (Author), Zhou, F. (Author), Zhou, S. (Author)
Format:	Article
Language:	English
Published:	MDPI 2022
Subjects:	Alzheimer disease amyotrophic lateral sclerosis Amyotrophic lateral sclerosis astrocyte biocompatibility biogenesis bioinformatics biological marker Biomarker cell differentiation disease duration down regulation endothelial progenitor cell gene control gene expression gene overexpression genetic transcription genetic transfection human microRNA microRNA 124a microRNA 132 microRNA 155 microRNA 206 microRNA 21 microRNA 338 microRNA 638 microRNA 663 microRNA 9 MiRNAs mitochondrial dynamics muscle atrophy muscle strength nerve cell degeneration nervous system development neurite outgrowth Neurodegeneration Noncoding RNA nonhuman nuclear reprogramming protein p53 regulatory T lymphocyte Review sclerosis single stranded RNA sirtuin 1 small untranslated RNA stoichiometry Therapy unclassified drug untranslated RNA upregulation
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The Biogenesis of miRNAs and Their Role in the Development of Amyotrophic Lateral Sclerosis

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