Quadruped Gait and Regulation of Apoptotic Factors in Tibiofemoral Joints following Intra-Articular rhPRG4 Injection in Prg4 Null Mice

Quadruped Gait and Regulation of Apoptotic Factors in Tibiofemoral Joints following Intra-Articular rhPRG4 Injection in Prg4 Null Mice

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Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome leads to diarthrodial joint arthropathy and is caused by the absence of lubricin (proteoglycan 4—PRG4), a surface-active mucinous glycoprotein responsible for lubricating articular cartilage. In this study, mice lacking the orthologous...

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Bibliographic Details
Main Authors: Badger, G.J (Author), Dickerson, E.E (Author), Elsaid, K.A (Author), Fredericks, A.M (Author), Jay, G.D (Author), Karamchedu, P.N (Author), Richendrfer, H. (Author), Schmidt, T.A (Author), Yang, D.S (Author), Zhang, L.X (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
arthritis
arthrosis
CACP
collagen hybridizing peptide
lubricin
PRG4
Prg4−/−
rhPRG4
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