A Novel NOX Inhibitor Treatment Attenuates Parkinson’s Disease-Related Pathology in Mouse Models

A Novel NOX Inhibitor Treatment Attenuates Parkinson’s Disease-Related Pathology in Mouse Models

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Parkinson’s disease (PD) is a progressive neurodegenerative motor disorder without an available therapeutic to halt the formation of Lewy bodies for preventing dopaminergic neuronal loss in the nigrostriatal pathway. Since oxidative-stress-mediated damage has been commonly reported as one of the mai...

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Bibliographic Details
Main Authors: Cabrera, G. (Author), Chung, J.H (Author), Ghosh, A.A (Author), Hernandez-Quijada, K. (Author), Kim, J.-K (Author), Kim, Y.-H (Author), Moon, S.H (Author), Moore, M. (Author), Ofori, K. (Author), Seo, J.B (Author), Verma, D.K (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
oxidative stress
protein aggregation
ROS inhibition
Thioflavin T
α-synuclein preformed fibrils
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