Metabolomic Profiling Reveals Protective Effects and Mechanisms of Sea Buckthorn Sterol against Carbon Tetrachloride-Induced Acute Liver Injury in Rats

Metabolomic Profiling Reveals Protective Effects and Mechanisms of Sea Buckthorn Sterol against Carbon Tetrachloride-Induced Acute Liver Injury in Rats

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The present study was designed to examine the efficacy and protection mechanisms of sea buckthorn sterol (SBS) against acute liver injury induced by carbon tetrachloride (CCl4 ) in rats. Five-week-old male Sprague-Dawley (SD) rats were divided into six groups and fed with saline (Group BG), 50% CCl4...

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Bibliographic Details
Main Authors: Guo, Y. (Author), Hong, E.-K (Author), Ma, J. (Author), Sheng, C. (Author), Yang, Y. (Author), Zhang, B. (Author), Zhang, D. (Author), Zhang, X. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
acute liver injury
alanine aminotransferase
Alanine Transaminase
animal
Animals
antioxidant
Antioxidants
carbon tetrachloride
Carbon Tetrachloride
Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury, Chronic
Chromatography, Liquid
Hippophae
lipid peroxidation
Lipid Peroxidation
liquid chromatography
liver
Liver
male
Male
metabolism
metabolomics
oxidative stress
Oxidative Stress
plant extract
Plant Extracts
rat
Rats
Rats, Sprague-Dawley
sea buckthorn sterol
Sprague Dawley rat
sterol
Sterols
tandem mass spectrometry
Tandem Mass Spectrometry
toxic hepatitis
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