Computational Analysis and Biological Activities of Oxyresveratrol Analogues, the Putative Cyclooxygenase-2 Inhibitors

Computational Analysis and Biological Activities of Oxyresveratrol Analogues, the Putative Cyclooxygenase-2 Inhibitors

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Polyphenols are a large family of naturally occurring phytochemicals. Herein, oxyresveratrol was isolated from ethanolic crude extracts of Artocarpus lacucha Buch.-Ham., and chemically modified to derive its lipophilic analogues. Biological screening assays showed their inhibitory potency against cy...

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Bibliographic Details
Main Authors: Duangdee, N. (Author), Jaiyong, P. (Author), Jongkon, N. (Author), Prateeptongkum, S. (Author), Seaho, B. (Author), Tayana, N. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
chemistry
cyclooxygenase 1
Cyclooxygenase 1
cyclooxygenase 2
Cyclooxygenase 2
cyclooxygenase 2 inhibitor
Cyclooxygenase 2 Inhibitors
human
Humans
inflammation
metabolism
molecular docking
Molecular Docking Simulation
plant extract
Plant Extracts
protein–ligand interactions
puag-haad
quantum chemistry
stilbene derivative
Stilbenes
stilbenoid
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