Merkel cell polyomavirus: Oncogenesis in a stable genome

Merkel cell polyomavirus (MCV) is the causative agent for the majority of Merkel cell carcinoma (MCC) cases. Polyomavirus-associated MCC (MCCP) is characterized by the integration of MCV DNA into the tumor genome and a low tumor mutational burden. In contrast, nonviral MCC (MCCN) is characterized by...

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Bibliographic Details
Main Authors: Ahmed, M.M (Author), Cushman, C.H (Author), Decaprio, J.A (Author)
Format: Article
Language:English
Published: MDPI 2022
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Online Access:View Fulltext in Publisher