Systemic and Lower Respiratory Tract Immunity to SARS-Cov-2 Omicron and Variants in Pediatric Severe COVID-19 and Mis-C

Systemic and Lower Respiratory Tract Immunity to SARS-Cov-2 Omicron and Variants in Pediatric Severe COVID-19 and Mis-C

Mucosal immunity plays an important role in the control of viral respiratory infections like SARS-CoV-2. While systemic immune responses against the SARS-2-CoV-2 have been studied in children, there is no information on mucosal antibody response, especially in the lower respiratory tract of children...

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Bibliographic Details
Main Authors: Irby, K. (Author), Khurana, S. (Author), Loftis, L.L (Author), Novak, T. (Author), Randolph, A.G (Author), Tang, J. (Author), Walker, T.C (Author), Zinter, M.S (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
adolescent
antibody response
Article
bronchoalveolar lavage fluid
child
coronavirus disease 2019
COVID-19
enzyme linked immunosorbent assay
HEK293 cell line
human
human cell
immunoglobulin A
immunoglobulin G
immunoglobulin M
lower respiratory tract
MIS-C
mucosal immunity
Mucosal immunity
Neutralization
neutralizing antibody
Omicron
Pediatric
pediatric multisystem inflammatory syndrome
reverse transcription polymerase chain reaction
SARS-CoV-2
SARS-CoV-2 lineage B.1.1.529
Severe acute respiratory syndrome coronavirus 2
Trachea
tracheal aspiration procedure
vaccination
Variants
virus detection
virus neutralization test
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