Novel insights into the roles and therapeutic implications of MUC1 oncoprotein via regulating proteins and non-coding RNAs in cancer

Novel insights into the roles and therapeutic implications of MUC1 oncoprotein via regulating proteins and non-coding RNAs in cancer

Mucin 1 (MUC1) is a heterodimeric transmembrane glycoprotein that protects epithelial cells in mammals. The transmembrane C-terminal subunit (MUC1-C) plays a crucial role in oncogenesis. As an oncoprotein, MUC1-C regulates a number of proteins that are associated with tumorigenesis by interacting wi...

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Bibliographic Details
Main Authors: Che, J. (Author), Han, Y. (Author), Kufe, D. (Author), Li, W. (Author), Li, X. (Author), Sun, C. (Author), Yao, X. (Author), Zheng, J. (Author)
Format: Article
Language:English
Published: Ivyspring International Publisher 2022
Subjects:
angiogenesis
apoptosis
breast cancer
cancer growth
cancer immunotherapy
cancer therapy
carcinogenesis
cell invasion
cell proliferation
cervical cancer cell line
circular ribonucleic acid
Clinical application
drug resistance
epithelial mesenchymal transition
esophageal squamous cell carcinoma cell line
gene expression regulation
human
immune evasion
long untranslated RNA
malignant neoplasm
microRNA
microRNA 1226
microRNA 125b
microRNA 1291
microRNA 145
microRNA 206
microRNA 29a
microRNA 326
microRNA 330 5p
microRNA 512 5p
microRNA 551b
microRNA136
MUC1
mucin 1
nanocarrier
Non-coding RNAs
nonhuman
ovary cancer
pancreas cancer
prostate carcinoma
protein expression
protein function
protein protein interaction
protein RNA binding
Proteins
regulator protein
Review
stomach cancer
transcription factor
unclassified drug
untranslated region
untranslated RNA
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