Characterization and modulation of surface charges to enhance extracellular vesicle isolation in plasma

Characterization and modulation of surface charges to enhance extracellular vesicle isolation in plasma

Extracellular vesicles (EVs) carry information inherited from parental cells, having significant potential for disease diagnosis. In blood, however, EVs are outnumbered >104-fold by low density lipoproteins (LDLs), yet similar in size and density. These fundamental disadvantages often cause LDL s...

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Bibliographic Details
Main Authors: Castro, C.M (Author), Cho, Y.K (Author), Lee, C.Y (Author), Lee, H. (Author), Woo, H.-K (Author)
Format: Article
Language:English
Published: Ivyspring International Publisher 2022
Subjects:
Article
buffer
Cancer
cation exchange
controlled study
depletion
electricity
elution
exosome
Extracellular vesicles
female
filtration
high density lipoprotein
human
human cell
hypothesis
ion exchange chromatography
isolation procedure
lipid composition
Lipoproteins
low density lipoprotein
messenger RNA
pH
physical parameters
physical phenomena
plasma
size exclusion chromatography
Size-exclusion
surface charge
Surface charge modulation
zeta potential
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