A rapid MCM-41 dispersive micro-solid phase extraction coupled with LC/MS/MS for quantification of ketoconazole and voriconazole in biological fluids

A rapid dispersive micro-solid phase extraction (D-μ-SPE) combined with LC/MS/MS method was developed and validated for the determination of ketoconazole and voriconazole in human urine and plasma samples. Synthesized mesoporous silica MCM-41 was used as sorbent in d-μ-SPE of the azole compounds fro...

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Bibliographic Details
Main Authors: Abd Aziz, N. (Author), Kamaruzaman, S. (Author), Loh, S.H (Author), Nur, H. (Author), Sanagi, M.M (Author), Wan Ibrahim, W.A (Author), Yahaya, N. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Ltd 2017
Subjects:
pH
Online Access:View Fulltext in Publisher
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