Hippocampal amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid GluA1 (AMPA GluA1) receptor subunit involves in learning and memory improvement following treatment with Centella asiatica extract in adolescent rats

Hippocampal amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid GluA1 (AMPA GluA1) receptor subunit involves in learning and memory improvement following treatment with Centella asiatica extract in adolescent rats

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Introduction: Centella asiatica is an herbal plant that contains phytochemicals that are widely believed to have positive effects on cognitive function. The adolescent stage is a critical development period for the maturation of brain processes that encompass changes in physical and psychological sy...

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Bibliographic Details
Main Authors: Abdullah, J.M (Author), Adenan, M.L (Author), Binti Mohd Yusuf Yeo, N.A (Author), Jaafar, H. (Author), Mohamad, H. (Author), Mohammed, F.R (Author), Muthuraju, S. (Author), Senik, M.H (Author), Tengku Muhammad, T.S (Author), Wong, J.H (Author), Yusof, S.R (Author), Zhang, J. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Ltd 2018
Subjects:
4 aminobutyric acid A receptor alpha1
adolescent
alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
AMPA receptor
animal
animal behavior
animal experiment
animal model
animal tissue
Animals
apoptosis
Article
Behavior, Animal
cell structure
Centella asiatica
Centella asiatica extract
cognition
controlled study
dose response
drug effect
escape latency
fluorescein isothiocyanate
fluorescence microscopy
GABA receptor
glutamate receptor 1
hippocampal CA1 region
hippocampal CA2 region
hippocampus
Hippocampus
immunohistochemistry
learning
Learning
learning and memory
lipocortin 5
locomotion
Locomotion
male
Male
memory
Memory
memory consolidation
memory test
metabolism
Models, Animal
Morris water maze test
nerve cell
nervous system development
Neurons
nonhuman
open field test
priority journal
propidium iodide assay
protein expression
rat
Rats
Rats, Wistar
Receptors, AMPA
reversal learning
spatial learning
spatial memory
triterpene
Triterpenes
Wistar rat
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