Detection and Analysis of Proteins Modified by O-Linked N-Acetylglucosamine

Detection and Analysis of Proteins Modified by O-Linked N-Acetylglucosamine

O-GlcNAc is a common post-translational modification of nuclear, mitochondrial, and cytoplasmic proteins that regulates normal physiology and the cell stress response. Dysregulation of O-GlcNAc cycling is implicated in the etiology of type II diabetes, heart failure, hypertension, and Alzheimer'...

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Bibliographic Details
Main Authors: Fahie, K. (Author), Fernandes, S.M (Author), Hart, G.W (Author), Narayanan, B. (Author), Reeves, R. (Author), Zachara, N.E (Author), Zahra, F. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Inc. 2021
Subjects:
Acetylglucosamine
affinity chromatography
analysis
animal cell
Article
beta n acetylhexosaminidase
cell nucleus
Cell Nucleus
clinical protocol
controlled study
detection
Diabetes Mellitus, Type 2
galactosyltransferase
glycosylation
Glycosylation
human
Humans
mammal cell
metabolism
monolayer culture
n acetylglucosamine
non insulin dependent diabetes mellitus
nonhuman
O-GlcNAc
O-linked
polyacrylamide gel electrophoresis
protein analysis
protein antibody
protein glycosylation
protein modification
protein processing
Protein Processing, Post-Translational
signal transduction
stoichiometry
wheat germ agglutinin
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