Multiparametric Analyses of Hepatocellular Carcinoma Somatic Mouse Models and Their Associated Tumor Microenvironment

Multiparametric Analyses of Hepatocellular Carcinoma Somatic Mouse Models and Their Associated Tumor Microenvironment

The rising incidence and increasing mortality of hepatocellular carcinoma (HCC), combined with its high tumor heterogeneity, lack of druggable targets, and tendency to develop resistance to chemotherapeutics, make the development of better models for this cancer an urgent challenge. To better mimic...

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Bibliographic Details
Main Authors: Akkari, L. (Author), de Groot, M.H.P (Author), de Wit, N. (Author), Klarenbeek, S. (Author), Ramirez, C.F.A (Author), Taranto, D. (Author), Van Baalen, M. (Author), Vegna, S. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Inc. 2021
Subjects:
animal
animal cell
animal experiment
animal model
animal tissue
Animals
article
cancer growth
Carcinoma, Hepatocellular
disease model
Disease Models, Animal
ex vivo study
flow cytometry
fluorescence activated cell sorting
genetic transcription
genetics
hepatocellular carcinoma
hepatocellular carcinoma cell line
histopathology
hydrodynamics
immunocompetent cell
immunofluorescence
immunohistochemistry
intravenous drug administration
liver cell carcinoma
Liver Neoplasms
liver tumor
male
Mice
mouse
mouse model
multi-parametric flow cytometry
nonhuman
nuclear magnetic resonance imaging
phenotype
protein analysis
somatic cell genetics
somatic murine models
tail vein
tumor growth
tumor microenvironment
Tumor Microenvironment
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