Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses

Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses

Studies in various tissues have revealed a central role of metabolic pathways in regulating adult stem cell function in tissue regeneration and tumor initiation. The unique metabolic dependences or preferences of adult stem cells, therefore, are emerging as a new category of therapeutic target. Rece...

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Bibliographic Details
Main Authors: Cheng, C.-W (Author), Gebert, N. (Author), Lewis, C.A (Author), Ori, A. (Author), Rahman, S. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
3 hydroxybutyric acid
Article
cell isolation
cell metabolism
cell population
crypt cell
enzyme assay
fluorescence activated cell sorting
gene cluster
gene expression
gene expression profiling
Gene Expression Profiling
genetics
glutamate synthase (NADH)
liquid chromatography-mass spectrometry
metabolic fingerprinting
Metabolic Networks and Pathways
metabolism
metabolite
nicotinamide adenine dinucleotide
nonhuman
protein purification
proteome
Proteome
proteomics
Proteomics
RNA sequencing
stem cell
transcriptome
Transcriptome
transcriptomics
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