Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses

Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses

Studies in various tissues have revealed a central role of metabolic pathways in regulating adult stem cell function in tissue regeneration and tumor initiation. The unique metabolic dependences or preferences of adult stem cells, therefore, are emerging as a new category of therapeutic target. Rece...

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Bibliographic Details
Main Authors:	Cheng, C.-W (Author), Gebert, N. (Author), Lewis, C.A (Author), Ori, A. (Author), Rahman, S. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	3 hydroxybutyric acid Article cell isolation cell metabolism cell population crypt cell enzyme assay fluorescence activated cell sorting gene cluster gene expression gene expression profiling Gene Expression Profiling genetics glutamate synthase (NADH) liquid chromatography-mass spectrometry metabolic fingerprinting Metabolic Networks and Pathways metabolism metabolite nicotinamide adenine dinucleotide nonhuman protein purification proteome Proteome proteomics Proteomics RNA sequencing stem cell transcriptome Transcriptome transcriptomics
Online Access:	View Fulltext in Publisher

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