Expeditious Extraction of Histones from Limited Cells or Tissue Samples and Quantitative Top-Down Proteomic Analysis

Histones are the primary protein component of chromatin and are involved in virtually all DNA-templated processes. Histones are abundantly post-translationally modified by a variety of chromatin-modifying machinery. These post-translational modifications (PTMs) are recognized by a range of “reader”...

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Bibliographic Details
Main Authors: Holt, M.V (Author), Wang, T. (Author), Young, N.L (Author)
Format: Article
Language:English
Published: Blackwell Publishing Inc. 2021
Subjects:
DNA
Online Access:View Fulltext in Publisher