CRISPR Genome Editing Made Easy Through the CHOPCHOP Website
The design of optimal guide RNA (gRNA) sequences for CRISPR systems is challenged by the need to achieve highly efficient editing at the desired location (on-target editing) with minimal editing at unintended locations (off-target editing). Although laboratory validation should ideally be used to de...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Blackwell Publishing Inc.
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |