Ultrafast Sodium Imaging of the Axon Initial Segment of Neurons in Mouse Brain Slices

Ultrafast Sodium Imaging of the Axon Initial Segment of Neurons in Mouse Brain Slices

Monitoring Na+ influx in the axon initial segment (AIS) at high spatial and temporal resolution is fundamental to understanding the generation of an action potential (AP). Here, we present protocols to obtain this measurement, focusing on the AIS of layer 5 (L5) somatosensory cortex pyramidal neuron...

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Bibliographic Details
Main Authors: Blömer, L.A (Author), Canepari, M. (Author), Filipis, L. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Inc. 2021
Subjects:
action potential
animal
animal tissue
Animals
Article
axon
axon initial segment
Axon Initial Segment
Axons
bleaching
brain slice
calibration
controlled study
data analysis
metabolism
Mice
molecular imaging
mouse
nerve cell
Neurons
nonhuman
priority journal
process optimization
pyramidal nerve cell
pyramidal neuron
sodium
Sodium
sodium channel
Sodium Channels
sodium imaging
somatosensory cortex
Somatosensory Cortex
voltage gated sodium channel
voltage-gated sodium channels
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