In Vivo Phage Display as a Biomarker Discovery Tool for the Complex Neural Injury Microenvironment

In Vivo Phage Display as a Biomarker Discovery Tool for the Complex Neural Injury Microenvironment

The heterogeneous injury pathophysiology of traumatic brain injury (TBI) is a barrier to developing highly sensitive and specific diagnostic tools. Phage display, a protein‒protein screening technique routinely used in drug development, has the potential to be a powerful biomarker discovery tool for...

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Bibliographic Details
Main Authors: Martinez, B.I (Author), Stabenfeldt, S.E (Author)
Format: Article
Language:English
Published: Blackwell Publishing Inc. 2021
Subjects:
animal
animal experiment
animal model
animal tissue
Animals
Article
bacteriophage
Bacteriophages
bioinformatics
biological marker
Biomarkers
bioprospecting
Bioprospecting
blood brain barrier
cell surface display
Cell Surface Display Techniques
controlled cortical impact
craniotomy
domain antibody fragment
domain antibody phage
Escherichia coli
experimental traumatic brain injury
genetics
high throughput sequencing
Mice
molecular evolution
mouse
mouse model
next generation sequencing
nonhuman
peptide library
Peptide Library
phage display
phage titer
priority journal
protein motif
Sanger sequencing
traumatic brain injury
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