Broad white matter impairment in multiple system atrophy

Broad white matter impairment in multiple system atrophy

Multiple system atrophy (MSA) is a rare neurodegenerative disorder characterized by the widespread aberrant accumulation of α-synuclein (α-syn). MSA differs from other synucleinopathies such as Parkinson's disease (PD) in that α-syn accumulates primarily in oligodendrocytes, the only source of...

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Bibliographic Details
Main Authors: Brefel-Courbon, C. (Author), Del Campo, N. (Author), Galitzky, M. (Author), Joshi, S. (Author), Narr, K.L (Author), Ory-Magne, F. (Author), Pavy-LeTraon, A. (Author), Péran, P. (Author), Phillips, O. (Author), Rascol, O. (Author), Singh, M.K (Author), Thalamas, C. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
aged
Aged
alpha synuclein
Article
axial diffusivity
clinical article
cognition
controlled study
diagnostic imaging
diffusion tensor imaging
diffusion weighted imaging
echo planar imaging
female
Female
fractional anisotropy
human
Humans
image processing
in vivo study
Magnetic Resonance Imaging
male
Male
mean diffusivity
middle aged
Middle Aged
Mini Mental State Examination
MRI
multiple system atrophy
Multiple System Atrophy
neuroimaging
nuclear magnetic resonance imaging
oligodendroglia
Parkinson disease
pathophysiology
priority journal
procedures
radial diffusivity
Shy Drager syndrome
three-dimensional imaging
Unified Parkinson Disease Rating Scale
white matter
White Matter
white matter lesion
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