Broad white matter impairment in multiple system atrophy

Broad white matter impairment in multiple system atrophy

Multiple system atrophy (MSA) is a rare neurodegenerative disorder characterized by the widespread aberrant accumulation of α-synuclein (α-syn). MSA differs from other synucleinopathies such as Parkinson's disease (PD) in that α-syn accumulates primarily in oligodendrocytes, the only source of...

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Main Authors:	Brefel-Courbon, C. (Author), Del Campo, N. (Author), Galitzky, M. (Author), Joshi, S. (Author), Narr, K.L (Author), Ory-Magne, F. (Author), Pavy-LeTraon, A. (Author), Péran, P. (Author), Phillips, O. (Author), Rascol, O. (Author), Singh, M.K (Author), Thalamas, C. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adult aged Aged alpha synuclein Article axial diffusivity clinical article cognition controlled study diagnostic imaging diffusion tensor imaging diffusion weighted imaging echo planar imaging female Female fractional anisotropy human Humans image processing in vivo study Magnetic Resonance Imaging male Male mean diffusivity middle aged Middle Aged Mini Mental State Examination MRI multiple system atrophy Multiple System Atrophy neuroimaging nuclear magnetic resonance imaging oligodendroglia Parkinson disease pathophysiology priority journal procedures radial diffusivity Shy Drager syndrome three-dimensional imaging Unified Parkinson Disease Rating Scale white matter White Matter white matter lesion
Online Access:	View Fulltext in Publisher

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