Cardiorespiratory fitness, hippocampal subfield volumes, and mnemonic discrimination task performance in aging

Cardiorespiratory fitness, hippocampal subfield volumes, and mnemonic discrimination task performance in aging

Aging and exercise have opposing effects on mnemonic discrimination task performance, which putatively taxes pattern separation mechanisms reliant on the dentate gyrus (DG) subfield of the hippocampus. In young adults, increasing cardiorespiratory fitness (CRF) has been shown to improve mnemonic dis...

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Bibliographic Details
Main Authors: Kern, K.L (Author), Schon, K. (Author), Storer, T.W (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
aerobic exercise
aged
Aged
Aged, 80 and over
aging
Aging
anatomy and histology
article
body volume
CA3 Region, Hippocampal
cardiorespiratory fitness
Cardiorespiratory Fitness
clinical trial
dentate gyrus
Dentate Gyrus
diagnostic imaging
discrimination learning
Discrimination Learning
entorhinal cortex
female
Female
hippocampal CA3 region
hippocampus
human
human experiment
Humans
Magnetic Resonance Imaging
male
Male
memory
middle aged
Middle Aged
mnemonic discrimination
MRI
neuroimaging
nuclear magnetic resonance imaging
pattern separation
physical activity
physiology
sex factor
Sex Factors
subiculum
task performance
Task Performance and Analysis
treadmill test
very elderly
young adult
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