An empirical comparison of univariate versus multivariate methods for the analysis of brain–behavior mapping

An empirical comparison of univariate versus multivariate methods for the analysis of brain–behavior mapping

Lesion symptom mapping (LSM) tools are used on brain injury data to identify the neural structures critical for a given behavior or symptom. Univariate lesion symptom mapping (ULSM) methods provide statistical comparisons of behavioral test scores in patients with and without a lesion on a voxel by...

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Bibliographic Details
Main Authors: Baldo, J.V (Author), Dronkers, N.F (Author), Herron, T.J (Author), Ivanova, M.V (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
aged
Aged
Aged, 80 and over
analysis of variance
Analysis of Variance
anatomical concepts
anomic aphasia
aphasia
Article
ataxic aphasia
brain cortex
brain mapping
Brain Mapping
brain region
brain–behavior relationships
Cerebral Cortex
cerebrovascular accident
comparative study
computer simulation
Computer Simulation
conduction aphasia
cortical sensory aphasia
data accuracy
data analysis software
diagnostic imaging
false negative result
false positive result
female
Female
global aphasia
human
Humans
image processing
Image Processing, Computer-Assisted
image reconstruction
intermethod comparison
language
left hemisphere
lesion symptom mapping
lesion volume
Magnetic Resonance Imaging
major clinical study
male
Male
middle aged
Middle Aged
multivariate
multivariate lesion symptom mapping
nerve cell network
Nerve Net
noise
nuclear magnetic resonance imaging
pathology
pathophysiology
priority journal
procedures
sample size
simulation
speech and language
statistically significant result
stroke
Stroke
stroke patient
transcortical motor aphasia
transcortical sensory aphasia
univariate lesion symptom mapping
very elderly
VLSM
Western aphasia battery
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