Reorganization of functional brain network architecture in chronic osteoarthritis pain

Reorganization of functional brain network architecture in chronic osteoarthritis pain

Osteoarthritis (OA) manifests with chronic pain, motor impairment, and proprioceptive changes. However, the role of the brain in the disease is largely unknown. Here, we studied brain networks using the mathematical properties of graphs in a large sample of knee and hip OA (KOA, n = 91; HOA, n = 23)...

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Bibliographic Details
Main Authors: Apkarian, A.V (Author), Baliki, M. (Author), Barroso, J. (Author), Galhardo, V. (Author), Reis, A.M (Author), Schnitzer, T.J (Author), Wakaizumi, K. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
aged
Aged
arthralgia
Arthralgia
Article
blood oxygenation
brain cortex
brain networks
brain region
brain topology
cerebellum
Cerebral Cortex
chronic pain
Chronic Pain
cingulo opercular network
cohort analysis
complication
connectome
Connectome
controlled study
diagnostic imaging
female
Female
frontoparietal network
functional magnetic resonance imaging
graph properties
hip osteoarthritis
human
Humans
insula
knee osteoarthritis
Magnetic Resonance Imaging
major clinical study
male
Male
mathematical analysis
middle aged
Middle Aged
nerve cell network
Nerve Net
nuclear magnetic resonance imaging
osteoarthritis
Osteoarthritis, Hip
Osteoarthritis, Knee
pain intensity
parahippocampal gyrus
pathophysiology
priority journal
total arthroplasty
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