Genetic scores for adult subcortical volumes associate with subcortical volumes during infancy and childhood

Genetic scores for adult subcortical volumes associate with subcortical volumes during infancy and childhood

Individual differences in subcortical brain volumes are highly heritable. Previous studies have identified genetic variants that underlie variation in subcortical volumes in adults. We tested whether those previously identified variants also affect subcortical regions during infancy and early childh...

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Bibliographic Details
Main Authors: Ikram, M.A (Author), Jansen, P.R (Author), Labrecque, J.A (Author), Lamballais, S. (Author), White, T. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
amygdala
Amygdala
anatomy and histology
article
biological variation
Biological Variation, Population
Birth Cohort
brain stem
Brain Stem
caudate nucleus
child
Child
childhood
cohort analysis
controlled study
corpus striatum
Corpus Striatum
diagnostic imaging
echography
female
Female
genetic risk score
genetic variability
genetics
genome-wide association study
Genome-Wide Association Study
globus pallidus
human
Humans
infancy
infant
Infant
Infant, Newborn
Magnetic Resonance Imaging
major clinical study
male
Male
mediation analysis
MRI
multifactorial inheritance
Multifactorial Inheritance
newborn
nuclear magnetic resonance imaging
polygenic scores
postnatal development
prenatal development
Prospective Studies
prospective study
putamen
school child
subcortical volume
thalamus
Thalamus
Ultrasonography
ultrasound
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