Age-related estimates of aggregate g-ratio of white matter structures assessed using quantitative magnetic resonance neuroimaging

Age-related estimates of aggregate g-ratio of white matter structures assessed using quantitative magnetic resonance neuroimaging

The g-ratio, defined as the inner-to-outer diameter of a myelinated axon, is associated with the speed of nerve impulse conduction, and represents an index of axonal myelination and integrity. It has been shown to be a sensitive and specific biomarker of neurodevelopment and neurodegeneration. Howev...

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Bibliographic Details
Main Authors: Bergeron, C.M (Author), Bouhrara, M. (Author), Ferrucci, L. (Author), Khattar, N. (Author), Kim, R.W (Author), Melvin, D. (Author), Qian, W. (Author), Resnick, S.M (Author), Spencer, R.G (Author), Zukley, L.M (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
age
Age Factors
aged
Aged
Aged, 80 and over
aggregate g ratio
aggregate g-ratio
aging
Aging
Article
axon
Axons
brain mapping
brain region
capsula interna
cerebrospinal fluid
cohort analysis
controlled study
corpus callosum
diagnostic imaging
diffusion weighted imaging
excitation
female
Female
frontal lobe
human
human development
Human Development
human experiment
Humans
image registration
image segmentation
inferior longitudinal fasciculus
laboratory test
Magnetic Resonance Imaging
male
Male
middle aged
Middle Aged
Mini Mental State Examination
nerve conduction
nervous system parameters
neuroimaging
Neuroimaging
normal aging
nuclear magnetic resonance imaging
occipital lobe
occipitofrontal fasciculus
parietal lobe
physiology
priority journal
procedures
pyramidal tract
quantitative MRI
temporal lobe
very elderly
white matter
White Matter
young adult
Young Adult
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