Selective morphological and volumetric alterations in the hippocampus of children exposed in utero to gestational diabetes mellitus

Selective morphological and volumetric alterations in the hippocampus of children exposed in utero to gestational diabetes mellitus

Prior epidemiological studies have found that in utero exposure to gestational diabetes mellitus (GDM) is associated with increased risk for neurodevelopmental disorders. However, brain alterations associated with GDM are not known. The hippocampus is pivotal for cognition and emotional regulation....

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Bibliographic Details
Main Authors: Alves, J.M (Author), Chow, T. (Author), Clark, K.A (Author), Luo, S. (Author), Lynch, K.M (Author), Page, K.A (Author), Toga, A.W (Author), Xiang, A.H (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
Article
brain size
CA1 Region, Hippocampal
child
Child
developmental programming
Diabetes, Gestational
diagnostic imaging
electronic medical record
female
Female
gestational diabetes
glucose
glucose blood level
gray matter volume
hippocampal CA1 region
hippocampal shape analysis
hippocampal subfield analysis
hippocampus
Hippocampus
human
Humans
left hippocampus
Magnetic Resonance Imaging
major clinical study
male
Male
morphology
neuroimaging
nuclear magnetic resonance imaging
oral glucose tolerance test
pathology
pregnancy
Pregnancy
pregnancy diabetes mellitus
prenatal exposure
Prenatal Exposure Delayed Effects
priority journal
retrospective study
right hippocampus
school child
sex difference
sex factor
Sex Factors
thickness
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