Early-stage Parkinson's disease: Abnormal nigrosome 1 and 2 revealed by a voxelwise analysis of neuromelanin-sensitive MRI

Early-stage Parkinson's disease: Abnormal nigrosome 1 and 2 revealed by a voxelwise analysis of neuromelanin-sensitive MRI

Previous pathologic studies evaluated the substantia nigra pars compacta (SNpc) of a limited number of idiopathic Parkinson's disease (IPD) patients with relatively longer disease durations. Therefore, it remains unknown which region of the SNpc is most significantly affected in early-stage IPD...

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Bibliographic Details
Main Authors: Kim, E.Y (Author), Noh, Y. (Author), Sung, Y.H (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
affine transform
aged
Aged
anterior commissure
Article
brain stem
cerebral peduncle
clinical article
Clinical Dementia Rating
cohort analysis
controlled study
diagnostic imaging
disease duration
dopaminergic nerve cell
female
Female
hand movement
Hoehn and Yahr scale
human
Humans
least square analysis
left handedness
longitudinal study
magnetic resonance imaging
Magnetic Resonance Imaging
male
Male
measurement accuracy
melanin
Melanins
mesencephalon
metabolism
middle aged
Middle Aged
n (3 fluoropropyl) 2beta carboxymethoxy 3beta(4 iodophenyl)nortropane f 18
neuromelanin
neuroradiologist
nigrosome
nigrosome 1
nigrosome 2
nonparametric test
nuclear magnetic resonance imaging
Parkinson disease
Parkinson Disease
Pars Compacta
posterior commissure
priority journal
red nucleus
Retrospective Studies
retrospective study
right handedness
rigidity
substantia nigra pars compacta
susceptibility weighted imaging
tracer
unclassified drug
Unified Parkinson Disease Rating Scale
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