Delayed access to conscious processing in multiple sclerosis: Reduced cortical activation and impaired structural connectivity

Although multiple sclerosis (MS) is frequently accompanied by visuo-cognitive impairment, especially functional brain mechanisms underlying this impairment are still not well understood. Consequently, we used a functional MRI (fMRI) backward masking task to study visual information processing strati...

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Bibliographic Details
Main Authors:	Audoin, B. (Author), Gold, S.M (Author), Has Silemek, A.C (Author), Heesen, C. (Author), Kühn, S. (Author), Ranjeva, J.-P (Author), Stellmann, J.-P (Author), Weygandt, M. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	(un)consciousness adult Adult alemtuzumab anterior cingulate anterior visual system antidepressant agent Article backward masking beta interferon brain Brain brain cortex Cerebral Cortex cingulate gyrus clinical article clinical assessment cognitive defect Cognitive Dysfunction comparative study complication consciousness Consciousness controlled study corpus callosum diagnostic imaging diffusion tensor imaging Diffusion Tensor Imaging disease duration ego development Evoked Potentials, Visual Expanded Disability Status Scale female Female fingolimod fractional anisotropy fumaric acid functional connectivity functional magnetic resonance imaging glatiramer gray matter health care access human Humans information processing insula macular volume Magnetic Resonance Imaging male Male masking middle aged Middle Aged middle frontal gyrus mild cognitive impairment multiple sclerosis Multiple Sclerosis natalizumab nerve cell network Nerve Net nuclear magnetic resonance imaging occipital cortex occipital lobe ocrelizumab optic neuritis optic tract optical coherence tomography pathology pathophysiology pattern recognition Pattern Recognition, Visual Perceptual Masking physiology posterior cingulate precuneus primary motor cortex retina Retina rituximab striate cortex structural connectivity superior frontal gyrus symbol digit modalities test teriflunomide thalamus time factor Time Factors tractography unconsciousness visual acuity visual backward masking paradigm visual evoked potential visual information visual stimulation visual system
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Delayed access to conscious processing in multiple sclerosis: Reduced cortical activation and impaired structural connectivity

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