The stage-specifically accelerated brain aging in never-treated first-episode patients with depression

Depression associated with structural brain abnormalities is hypothesized to be related with accelerated brain aging. However, there is far from a unified conclusion because of clinical variations such as medication status, cumulative illness burden. To explore whether brain age is accelerated in ne...

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Bibliographic Details
Main Authors:	Chen, Y. (Author), Cheng, J. (Author), Fang, K. (Author), Han, S. (Author), Jiang, Y. (Author), Li, H. (Author), Li, S. (Author), Liu, L. (Author), Pang, J. (Author), Wang, C. (Author), Wei, Y. (Author), Yang, Z. (Author), Zhang, Y. (Author), Zheng, R. (Author), Zhou, B. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adolescent Adolescent adult Adult age Age Factors aging Aging, Premature article body weight brain brain age child Child clinical feature complication controlled study depression Depressive Disorder diagnostic imaging disease exacerbation Disease Progression female Female first-episode depression gender gray matter Gray Matter gray matter volume human Humans intermethod comparison machine learning Magnetic Resonance Imaging major clinical study male Male middle aged Middle Aged Models, Theoretical nuclear magnetic resonance imaging pathology prediction premature aging structural brain imaging theoretical model voxel based morphometry young adult Young Adult
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The stage-specifically accelerated brain aging in never-treated first-episode patients with depression

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