Function–structure coupling: White matter functional magnetic resonance imaging hyper-activation associates with structural integrity reductions in schizophrenia

Function–structure coupling: White matter functional magnetic resonance imaging hyper-activation associates with structural integrity reductions in schizophrenia

White matter (WM) microstructure deficit may be an underlying factor in the brain dysconnectivity hypothesis of schizophrenia using diffusion tensor imaging (DTI). However, WM dysfunction is unclear in schizophrenia. This study aimed to investigate the association between structural deficits and fun...

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Bibliographic Details
Main Authors: Duan, M. (Author), He, H. (Author), Huang, H. (Author), Jiang, Y. (Author), Li, S. (Author), Li, X. (Author), Luo, C. (Author), Song, X. (Author), Yao, D. (Author), Zhao, G. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
activation
adult
Adult
Article
behavior assessment
cognition
controlled study
diagnostic imaging
diffusion tensor imaging
Diffusion Tensor Imaging
disease duration
disease exacerbation
disease severity
emotion
female
Female
fMRI
fractional anisotropy
frontal
frontal cortex
functional magnetic resonance imaging
functional neuroimaging
Functional Neuroimaging
human
Humans
Magnetic Resonance Imaging
major clinical study
male
Male
measurement repeatability
middle aged
Middle Aged
motor activity
negative syndrome
neuropathology
nuclear magnetic resonance imaging
oscillation
pathology
pathophysiology
personality
reproducibility
schizophrenia
Schizophrenia
sensory analysis
temporal cortex
white matter
White Matter
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