Functional impairment-based segmentation of anterior cingulate cortex in depression and its relationship with treatment effects

In major depressive disorder (MDD), the anterior cingulate cortex (ACC) is widely related to depression impairment and antidepressant treatment response. The multiplicity of ACC subdivisions calls for a fine-grained investigation of their functional impairment and recovery profiles. We recorded rest...

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Bibliographic Details
Main Authors:	Chen, Z. (Author), Liu, H. (Author), Lu, Q. (Author), Pei, C. (Author), Shao, J. (Author), Wang, X. (Author), Yao, Z. (Author), Zhang, S. (Author), Zhang, Y. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adult Adult amygdala Amygdala anterior cingulate anterior cingulate cortex antidepressant agent antidepressive agents Article brain function cingulate gyrus clinical outcome connectome Connectome controlled study Depressive Disorder, Major diagnostic imaging dorsolateral prefrontal cortex Dorsolateral Prefrontal Cortex echo planar imaging escitalopram female Female fluoxetine functional connectivity functional magnetic resonance imaging functional MRI functional neuroimaging Gyrus Cinguli human Humans image segmentation k means clustering Magnetic Resonance Imaging major clinical study major depression major depressive disorders male Male middle aged Middle Aged monotherapy nuclear magnetic resonance imaging outcome assessment Outcome Assessment, Health Care pathophysiology prediction prefrontal cortex segmentation serotonin uptake inhibitor sertraline statistical analysis treatment outcome treatment response unsupervised machine learning young adult Young Adult
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Functional impairment-based segmentation of anterior cingulate cortex in depression and its relationship with treatment effects

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