Abnormal brain functional network dynamics in obsessive–compulsive disorder patients and their unaffected first-degree relatives

Abnormal brain functional network dynamics in obsessive–compulsive disorder patients and their unaffected first-degree relatives

We utilized dynamic functional network connectivity (dFNC) analysis to compare participants with obsessive–compulsive disorder (OCD) with their unaffected first-degree relative (UFDR) and healthy controls (HC). Resting state fMRI was performed on 46 OCD, 24 UFDR, and 49 HCs, along with clinical asse...

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Bibliographic Details
Main Authors: Chen, Q. (Author), Guo, Y. (Author), Peng, Z. (Author), Seger, C.A (Author), Wei, Z. (Author), Wu, X. (Author), Yang, Q. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
Article
auditory network
biological marker
brain
Brain
clinical assessment
clinical feature
clinical study
connectome
Connectome
controlled study
default mode network
diagnostic imaging
DSM-IV
dwell time
dynamic functional network connectivity
endophenotype
Endophenotypes
executive network
family
Family
female
Female
first-degree relative
first-degree relatives
functional connectivity
functional magnetic resonance imaging
human
Humans
intrinsic connectivity network
Magnetic Resonance Imaging
major clinical study
male
Male
nerve cell network
Nerve Net
nuclear magnetic resonance imaging
obsessive compulsive disorder
obsessive–compulsive disorder
Obsessive-Compulsive Disorder
pathophysiology
sensorimotor network
visual network
young adult
Young Adult
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