Early micro- and macrostructure of sensorimotor tracts and development of cerebral palsy in high risk infants

Infants born very preterm (VPT) are at high risk of motor impairments such as cerebral palsy (CP), and diagnosis can take 2 years. Identifying in vivo determinants of CP could facilitate presymptomatic detection and targeted intervention. Our objectives were to derive micro- and macrostructural meas...

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Main Authors:	Altaye, M. (Author), Arnsperger, A. (Author), Beiersdorfer, T. (Author), Bridgewater, K. (Author), Cahill, T. (Author), Cecil, K. (Author), Chandwani, R. (Author), Dietrich, K. (Author), Distler, C. (Author), Dudley, J. (Author), Georg, B. (Author), Grisby, C. (Author), Haas, L. (Author), Harpster, K. (Author), He, L. (Author), Holland, S.K (Author), Illapani, V.S.P (Author), Kirker, K. (Author), Kline, J.E (Author), Kline-Fath, B.M (Author), Lanier, M. (Author), Li, H. (Author), Merhar, S.L (Author), Muthig, G. (Author), Parikh, N.A (Author), Poindexter, B.B (Author), Russell, D. (Author), Tamm, L. (Author), Tepe, K. (Author), The Cincinnati Infant Neurodevelopment Early Prediction Study (CINEPS) Group (Author), Thompson, J. (Author), Tkach, J. (Author), Wang, H. (Author), Wang, J. (Author), Williams, B. (Author), Wineland, K. (Author), Wuertz, S. (Author), Wuest, D. (Author), Yuan, W. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	Article cerebral palsy Cerebral Palsy cohort analysis confounding variable constrained spherical deconvolution controlled study deconvolution diagnostic imaging diffusion MRI diffusion tensor imaging Diffusion Tensor Imaging diffusion weighted imaging early diagnosis female Female fiber orientation distribution gestational age high risk infant human Humans image analysis image segmentation infant Infant Infant, Extremely Premature Infant, Newborn intrarater reliability major clinical study male Male motoneuron neonatology nerve tract Neural Pathways neuroanatomy newborn nuclear magnetic resonance imaging pathology pathophysiology prematurity preterm birth Prospective Studies prospective study reproducibility risk Risk sensorimotor cortex Sensorimotor Cortex sensorimotor network structure analysis tractography white matter White matter White Matter
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Early micro- and macrostructure of sensorimotor tracts and development of cerebral palsy in high risk infants

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