Coupling relationship between glucose and oxygen metabolisms to differentiate preclinical Alzheimer's disease and normal individuals

Coupling relationship between glucose and oxygen metabolisms to differentiate preclinical Alzheimer's disease and normal individuals

The discovery of preclinical Alzheimer's disease (preAD) provides a wide time window for the early intervention of AD. The coupling relationships between glucose and oxygen metabolisms from hybrid PET/MRI can provide complementary information on the brain's physiological state for preAD. I...

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Bibliographic Details
Main Authors: Ding, C. (Author), Du, W. (Author), Han, Y. (Author), Jiang, J. (Author), Wang, L. (Author), Zhang, Q. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
aged
Aged
Alzheimer disease
Alzheimer Disease
amyloid beta protein
area under the curve
Article
biological marker
Biomarkers
brain
Brain
clinical article
connectome
Connectome
controlled study
correlation analysis
data analysis software
default mode network
Default Mode Network
diagnostic imaging
diagnostic test accuracy study
diagnostic value
disease classification
female
Female
florbetapir f 18
fluorodeoxyglucose f 18
Fluorodeoxyglucose F18
fractional amplitude of low-frequency fluctuation
functional magnetic resonance imaging
glucose
Glucose
glucose metabolism
human
Humans
image processing
Magnetic Resonance Imaging
male
Male
metabolism
middle aged
Middle Aged
nerve cell network
Nerve Net
neuropsychology
nuclear magnetic resonance imaging
oxidative coupling
oxygen
Oxygen
pathophysiology
position emission tomography
positron emission tomography
Positron-Emission Tomography
preclinical Alzheimer's disease
radiopharmaceutical agent
Radiopharmaceuticals
receiver operating characteristic
regional homogeneity
standardized uptake value ratio
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