Azacitidine regulates DNA methylation of GADD45γ in myelodysplastic syndromes
Background: Myelodysplastic syndrome (MDS) is a heterogeneous clonal disease originated from hematopoietic stem cells. Epigenetic studies had demonstrated that DNA methylation and histone acetylation were abnormal in MDS. Azacitidine is an effective drug in the treatment of demethylation. Methods: R...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
John Wiley and Sons Inc
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |