Identification of a stool long non-coding RNAs panel as a potential biomarker for early detection of colorectal cancer

Background: The feces of colorectal cancer (CRC) patients contain tumor colonocytes, which constantly shed into the lumen area. Therefore, stool evaluation can be considered as a rapid and low-risk way to directly determine the colon and rectum status. As long non-coding RNAs (lncRNAs) alterations a...

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Bibliographic Details
Main Authors:	Asadzadeh Aghdaei, H. (Author), Baghdar, K. (Author), Gharib, E. (Author), Hashemi, M. (Author), Jamshidi-Fard, A. (Author), Larki, P. (Author), Nayeri, Z. (Author), Nazemalhosseini-Mojarad, E. (Author), Rezasoltani, S. (Author), Sadeghi, A. (Author), Sadeghi, H. (Author)
Format:	Article
Language:	English
Published:	John Wiley and Sons Inc 2021
Subjects:	adult Adult advanced cancer Article biomarker Biomarkers, Tumor cancer staging cohort analysis colon cell colon polyp Colonic Polyps colorectal cancer Colorectal Neoplasms colorectal tumor controlled study early cancer diagnosis Early Detection of Cancer fecal colonocytes feces Feces feces analysis female Female gene expression gene expression regulation Gene Expression Regulation, Neoplastic gene sequence genetics human human cell Humans isolation and purification long non-coding RNAs long untranslated RNA long untranslated RNA CCAT1 long untranslated RNA CCAT2 long untranslated RNA H19 long untranslated RNA HOTAIR long untranslated RNA HULC long untranslated RNA MALAT1 long untranslated RNA MEG3 long untranslated RNA PCAT1 long untranslated RNA PTENP1 long untranslated RNA TUSC7 major clinical study male Male middle aged Middle Aged prediction quality control real time polymerase chain reaction reproducibility Reproducibility of Results RNA analysis RNA extraction RNA isolation RNA, Long Noncoding tumor marker unclassified drug validation study
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Identification of a stool long non-coding RNAs panel as a potential biomarker for early detection of colorectal cancer

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