Dysregulation of vitamin D synthesis pathway genes in colorectal cancer: A case-control study

Dysregulation of vitamin D synthesis pathway genes in colorectal cancer: A case-control study

Background: The cytochromes P450 are a superfamily of enzymes that control the synthesis of the biologically active form of vitamin D, 1,25-dihydroxyvitamin D3. These enzymes contribute to the formation of 1,25-dihydroxyvitamin D3, which starts with a 25-hydroxylation by CYP2R1 and CYP27A1 and a sub...

Full description

Bibliographic Details
Main Authors: Aghaei, N. (Author), Asadzadeh Aghdaei, H. (Author), Kamaliyan, Z. (Author), Mirfakhraie, R. (Author), Mohseni, R. (Author), Moshiri, A. (Author), Nazemalhosseini-Mojarad, E. (Author), Sadeghi, H. (Author), Sahebi, U. (Author), Zali, M.R (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
25-Hydroxyvitamin D3 1-alpha-Hydroxylase
adult
aged
Aged
Article
biosynthesis
calcidiol 1 monooxygenase
case control study
Case-Control Studies
cholestanetriol 26 monooxygenase
Cholestanetriol 26-Monooxygenase
colorectal cancer
Colorectal Neoplasms
colorectal tumor
controlled study
CYP27A1 gene
CYP27A1 protein, human
CYP27B1
CYP27B1 gene
CYP27B1 protein, human
CYP2R1
CYP2R1 gene
CYP2R1 protein, human
cytochrome P450 family 2
Cytochrome P450 Family 2
DNA extraction
female
Female
gene
gene expression
gene expression regulation
Gene Expression Regulation, Neoplastic
gene frequency
Gene Frequency
genetic association
genetic risk
genetics
genotype
human
human tissue
Humans
Iranian people
major clinical study
male
Male
metabolism
middle aged
Middle Aged
pathology
Polymorphism, Single Nucleotide
population research
real time polymerase chain reaction
single nucleotide polymorphism
single-nucleotide polymorphism
tetra primer amplification refractory mutation system polymerase chain reaction
upregulation
vitamin D
Vitamin D
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items