VE1 immunohistochemistry is an adjunct tool for detection of BRAFV600E mutation: Validation in thyroid cancer patients

VE1 immunohistochemistry is an adjunct tool for detection of BRAFV600E mutation: Validation in thyroid cancer patients

Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy among other endocrine tumors, and BRAFV600E is a frequent genetic mutation occurring in the disease. Although different molecular techniques, most importantly sequencing has been widely recognized as a gold standard but molecu...

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Bibliographic Details
Main Authors: Ansari, H.R (Author), Asif, M. (Author), Khan, M.S (Author), Rashid, F.A (Author), Sameer Aga, S. (Author), Sheikh, A.K (Author), Tabassum, S. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
amino acid substitution
Antibodies
antibody
Article
B Raf kinase
BRAF protein, human
BRAF V600E
cancer patient
cancer prognosis
cancer staging
cohort analysis
controlled study
diagnostic accuracy
dna mutational analysis
DNA Mutational Analysis
female
Female
formaldehyde
genetics
human
human tissue
Humans
immunohistochemistry
Immunohistochemistry
immunology
major clinical study
male
Male
middle aged
Middle Aged
missense mutation
mutation rate
mutational analysis
oncological parameters
papillary thyroid carcinoma
paraffin
pathology
predictive value
procedures
Proto-Oncogene Proteins B-raf
Retrospective Studies
retrospective study
sanger sequencing
Sanger sequencing
sensitivity and specificity
Thyroid Cancer, Papillary
Thyroid Neoplasms
thyroid papillary carcinoma
thyroid tumor
thyroidectomy
tissue fixation
tumor focality
validation study
VE1 immunohistochemistry
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