iTRAQ-based proteomic analysis of the molecular mechanisms and downstream effects of fatty acid synthase in osteosarcoma cells
Background: Fatty acid synthase (FASN) is a lipogenic enzyme that participates in tumor progression. We previously showed that FASN is dysregulated in OS malignancy, but the molecular mechanism(s) of these effects remained unclear. Methods: We examined differentially expressed proteins (DEPs) in FAS...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
John Wiley and Sons Inc
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |