Anti-citrullinated protein antibodies are associated with neutrophil extracellular trap formation in rheumatoid arthritis

Anti-citrullinated protein antibodies are associated with neutrophil extracellular trap formation in rheumatoid arthritis

Objectives: We evaluated the associations of anti-citrullinated protein antibodies (ACPAs) and serological and cytological levels of neutrophil extracellular trap (NET) formation in rheumatoid arthritis (RA) patients. Methods: Serum levels of myeloperoxidase-DNA and elastase-DNA complexes (NET remna...

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Bibliographic Details
Main Authors: Liang, X. (Author), Peng, W. (Author), Wang, W. (Author), Wu, S. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
affinity chromatography
aged
Aged
antibody isolation
antibody titer
anti-citrullinated protein antibodies
Anti-Citrullinated Protein Antibodies
Arthritis, Rheumatoid
Article
blood
case control study
Case-Control Studies
cell isolation
cell stimulation
complex formation
concentration response
controlled study
CXCL8 protein, human
cyclic citrullinated peptide antibody
cytology
density gradient centrifugation
DNA
drug effect
elastase
enzyme linked immunosorbent assay
extracellular trap
female
Female
fibroblast like synoviocyte cell
gene expression
human
human cell
Humans
IL6 protein, human
immunoglobulin G
Immunoglobulin G
immunoglobulin G antibody
in vitro study
inflammation
interleukin 6
interleukin 8
Interleukin-6
Interleukin-8
major clinical study
male
Male
messenger RNA
metabolism
microscopy
middle aged
Middle Aged
myeloperoxidase
neutrophil
neutrophil extracellular traps
Neutrophils
pathology
real time polymerase chain reaction
rheumatoid arthritis
serology
synoviocyte
Synoviocytes
tumor necrosis factor
Tumor Necrosis Factor-alpha
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