The relationship between plasma serglycin levels and the diagnosis of diabetic retinopathy

The relationship between plasma serglycin levels and the diagnosis of diabetic retinopathy

Background: Diabetic retinopathy (DR), a microvascular complication which is closely related to diabetes, remains the leading cause of vision loss around the world among older adults. Serglycin (SRGN) was known as a hematopoietic cell granule proteoglycan, exerting its function in the formation of m...

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Bibliographic Details
Main Authors: Han, Y. (Author), Wang, L. (Author), Wang, X. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
apoptosis
Apoptosis
Article
biomarker
blood
blood sampling
case control study
Case-Control Studies
cell line
Cell Line
cell proliferation
Cell Proliferation
comparative study
controlled study
cytology
Diabetes Mellitus, Type 2
diabetic retinopathy
Diabetic Retinopathy
diagnosis
diagnostic test accuracy study
disease course
drug effect
endothelium cell
experimental study
female
Female
gene expression
gene knockdown
genetics
glucose
Glucose
high-glucose diet
human
human cell
Humans
in vitro study
major clinical study
male
Male
messenger RNA
middle aged
Middle Aged
non insulin dependent diabetes mellitus
nonproliferative diabetic retinopathy
polymerase chain reaction
proliferative diabetic retinopathy
protein blood level
protein depletion
protein expression
protein serglycin
proteoglycan
Proteoglycans
retina cell
retinal pigment epithelium
Retinal Pigment Epithelium
sensitivity and specificity
serglycin
SRGN
unclassified drug
upregulation
vesicular transport protein
Vesicular Transport Proteins
Western blotting
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