Luteolin enhances the antitumor efficacy of oncolytic vaccinia virus that harbors IL-24 gene in liver cancer cells

Luteolin enhances the antitumor efficacy of oncolytic vaccinia virus that harbors IL-24 gene in liver cancer cells

Background: Interleukin 24 (IL-24) is an IL-10 family member and a secreted cytokine characterized by cancer-targeted toxicity and can activate apoptosis by sensitizing cancer cells to chemotherapy. Cytotoxic effects of luteolin on different types of cancer cells suppress their growth by acting on t...

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Bibliographic Details
Main Authors: Fang, H. (Author), Huang, B. (Author), Huang, F. (Author), Li, Q. (Author), Wang, C. (Author), Wang, Y. (Author), Xiao, B. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
animal
animal cell
animal experiment
animal tissue
Animals
antineoplastic activity
antineoplastic agent
Antineoplastic Agents
apoptosis
Apoptosis
Article
Bagg albino mouse
cancer inhibition
Cell Line, Tumor
cell survival
Cell Survival
cell viability
controlled study
drug effect
drug efficacy
drug potentiation
drug screening
female
Female
flow cytometry
genetics
human
human cell
Humans
IL 24 gene
IL-24 gene
in vivo study
interleukin 24
interleukin derivative
interleukin-24
Interleukins
liver cancer
Liver Neoplasms
liver tumor
luteolin
Luteolin
MHCC97-H cell line
Mice, Inbred BALB C
monotherapy
mouse
mouse model
MTT assay
nonhuman
oncolytic vaccinia virus
oncolytic virotherapy
Oncolytic Virotherapy
oncolytic virus
Oncolytic Viruses
pathology
procedures
treatment duration
tumor cell line
tumor xenograft
Vaccinia virus
Western blotting
Xenograft Model Antitumor Assays
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