Prognostic value of BRAF/MIR-17 signature and B-Raf protein expression in patients with colorectal cancer: A pilot study

Prognostic value of BRAF/MIR-17 signature and B-Raf protein expression in patients with colorectal cancer: A pilot study

Background: Despite the recent improvement in colorectal cancer (CRC) treatment, it still has a poor prognosis with a low survival rate. Genetic and epigenetic mechanisms have proved to play a substantial role in CRC tumorigenesis and progression. According to Gene Ontology and TargetScan analyses,...

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Bibliographic Details
Main Authors: Abu AlSel, B.T (Author), Fawzy, M.S (Author), Ibrahiem, A.T (Author), Toraih, E.A (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
aged
Aged
Article
B Raf kinase
Biomarkers, Tumor
BRAF
BRAF gene
BRAF protein, human
cancer grading
cancer localization
cancer prognosis
cancer survival
colorectal cancer
Colorectal Neoplasms
colorectal tumor
controlled study
disease free survival
female
Female
gene expression
gene expression regulation
Gene Expression Regulation, Neoplastic
genetics
human
human tissue
Humans
IHC
immunohistochemistry
lymph node metastasis
Lymphatic Metastasis
major clinical study
male
Male
metabolism
microRNA
MicroRNAs
middle aged
Middle Aged
MIR 17 gene
miR-17
MIRN17 microRNA, human
mortality
overall survival
pathology
Pilot Projects
pilot study
prognosis
Prognosis
prognostic assessment
protein expression
Proto-Oncogene Proteins B-raf
qPCR
real time polymerase chain reaction
Retrospective Studies
retrospective study
survival rate
Survival Rate
tumor gene
tumor marker
tumor volume
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