Long non-coding RNA UCA1 correlates with elevated disease severity, Th17 cell proportion, inflammatory cytokines, and worse prognosis in acute ischemic stroke patients

Long non-coding RNA UCA1 correlates with elevated disease severity, Th17 cell proportion, inflammatory cytokines, and worse prognosis in acute ischemic stroke patients

Background: This study aimed to explore the association of long non-coding RNA urothelial carcinoma-associated 1 (lncRNA UCA1) expression with disease severity, inflammation, and prognosis in acute ischemic stroke (AIS) patients. Methods: The lncRNA UCA1 expression of blood CD4+ T cells from 160 fir...

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Bibliographic Details
Main Authors: Chen, L. (Author), Feng, Q. (Author), Niu, X. (Author), Ren, B. (Author), Song, Z. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
acute ischemic stroke
adult
age distribution
aged
Aged
Article
blood
brain ischemia
case control study
Case-Control Studies
CD4+ T lymphocyte
controlled study
correlation analysis
cytokine
disease severity
enzyme linked immunosorbent assay
female
Female
flow cytometry
gene expression
Gene Expression
gene function
genetics
human
Humans
ICAM1 protein, human
IL6 protein, human
inflammation
Inflammation
intercellular adhesion molecule 1
Intercellular Adhesion Molecule-1
interleukin 17
interleukin 6
Interleukin-17
Interleukin-6
Ischemic Stroke
Long non-coding RNA urothelial carcinoma-associated 1
long untranslated RNA
long untranslated RNA UCA1
major clinical study
male
Male
middle aged
Middle Aged
mortality
National Institutes of Health Stroke Scale
pathology
prognosis
Prognosis
prognostic assessment
real time reverse transcription polymerase chain reaction
recurrence free survival
risk assessment
risk factor
RNA, Long Noncoding
severity of illness index
Severity of Illness Index
sex difference
stroke patient
Th17 cell
Th17 Cells
UCA1 RNA, human
unclassified drug
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