Expression profiling and bioinformatics analysis of exosomal long noncoding RNAs in patients with myasthenia gravis by RNA sequencing

Expression profiling and bioinformatics analysis of exosomal long noncoding RNAs in patients with myasthenia gravis by RNA sequencing

Background: Myasthenia gravis (MG) is an autoimmune disease mediated by acetylcholine receptor antibodies. Exosomes were shown to be involved in the immune modulation and autoimmune diseases. However, the expression and function of exosomal long noncoding RNAs (lncRNAs) in MG are still unclear. Meth...

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Bibliographic Details
Main Authors: Chen, T.-T (Author), Lu, W. (Author), Lu, Y. (Author), Wang, C.-F (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
Adult
Article
autoimmune thyroiditis
bioinformatics
biology
biomarkers
blood
clinical article
Computational Biology
controlled study
down regulation
exosome
Exosomes
female
Female
gene expression profiling
Gene Expression Profiling
gene expression regulation
Gene Expression Regulation
gene function
gene ontology
Gene Ontology
gene regulatory network
Gene Regulatory Networks
genetics
high throughput
high throughput sequencing
human
Humans
long noncoding RNA
long untranslated RNA
male
Male
messenger RNA
metabolism
microRNA
myasthenia gravis
Myasthenia Gravis
pathogenesis
real time polymerase chain reaction
reproducibility
Reproducibility of Results
RNA, Long Noncoding
sequence analysis
Sequence Analysis, RNA
signal transduction
T lymphocyte receptor
upregulation
validation study
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